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Oral zinc sulphate causes murine hair hypopigmentation and is a potent inhibitor of eumelanogenesis in vivo

Nitrosative stress is also present, as illustrated by markers of nitrosative stress such as increased NOS and NO (182, 297), peroxynitrite (182, 297), elevated NF- production (182), and nitrate after exercise (182, 297)

Nevertheless, a complexity that remains, is the fact that many TAAR1 agonists have lower selectivity for TAAR1 than other monoaminergic G-protein coupled receptors, increasing the risk of off-target effects