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PMID: 41790500 Pathol Res Pract2025 Oct 17;276:156273

10.5489/cuaj.8685 5 AshkarA.SosnikA.Davidovich-PinhasM

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429,430,431,432,433 The mechanism of enhanced glycolysis involves the activation of pyruvate kinase isoenzyme M2 (PKM2), which triggers downstream inflammatory factors in a hypoxia-inducible factor 1 (HIF-1)-dependent manner