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Laparoscopy, a minimally invasive surgical procedure, allows direct examination of the outside of the reproductive organs for external fibroids or other abnormalities

After ingestion by the louse, LBRF spirochetes pass from the midgut to the hemolymph where they multiply and persist for the ~3-week lifespan of the louse

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Unrestrained replication fork progression in HRASV12- or cyclin E1-overexpressing cells depends on proteins involved in restarting R-loop-stalled forks The unrestrained replication fork progression induced by PARP inhibition in cells treated with R-loop-inducing drugs is dependent on the MUS81-EME1 endonuclease, the DNA helicase RECQ1, the DNA ligase IV (LIG4), and the transcription elongation factor ELL, among others 14,27