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Evidence for penile endothelial dysfunction, CSMC fibrosis, and neural injury in varicocele is derived predominantly from animal models, gene-knockout systems, and extrapolation from broader ED models, including diabetes, vascular injury, aging, and cavernous nerve injury

Extracellular matrix produced by bone marrow stromal cells and by their derivative, SB623 cells, supports neural cell growth

Improved neurodevelopmental outcomes at 5.5 Years of age in children who received bovine milk fat globule membrane and lactoferrin in infant formula through 12 Months: a randomized controlled trial

(Strong recommendation, high level of evidence) Summary of Evidence Gastrointestinal symptoms alone cannot accurately differentiate CD from other common gastrointestinal disorders (e.g., 2050% of patients with CD fulfilled Rome criteria for irritable bowel syndrome)