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Acknowledgements The authors are grateful for the technical assistance and support provided by Margarita Ecay, Neira Sinz, and Sara Arcelus, and the manuscript review of Katarina Smiljanec from ADM Regulatory and Scientific Affairs

172 In one study that included 92 women and 46 men undergoing assisted reproductive treatment and 161 controls, MTHFR mutations were correlated with poor in vitro fertilization outcomes and embryonic chromosomal abnormalities

Consequently, vitamin D deficiency is strongly implicated in ovarian pathologies like PCOS and diminished ovarian reserve (99)

Glutathione S-transferases play important roles in resistance to DDT and other groups of insecticides