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Ulcerative colitis Ulcerative colitis (UC), a chronic bowel disease with immune disorders involving the colon and rectum, has contributing pathogenic factors characterized by individual heterogeneity, such as environmental factors, genetic susceptibility, and immune imbalances

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Initial inhibitor screens were conducted in 200 l volumes in 96 well plates with 50 M inhibitor, 100 M NADPH, and 5 nM TGR in 0.1 M potassium phosphate (pH 7.4), 10 mM EDTA with a preincubation step of 15 min

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