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Herein, the SP was engineered with macrophage cell membranes (MCMs) to avoid immune clearance and increase the targeted accumulation of the SP at disease sites

3 Diagnosing metabolic disorders using microneedles and nanoparticles Recent developments in point-of-care diagnostics have increased the significance of combining microneedles with nanoparticles to facilitate the extraction and measurement of metabolic syndrome-related biomarkers from interstitial fluid (ISF) in a timely, accurate, and minimally damaging manner[75]

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We classified non-eclipsed particles as well-folded (flat or twisted) or poorly folded, with the latter including irregular arrays and a recurrent mis-twisted conformation in which one nucleosome is displaced from its stack (Fig