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This highlights not only its diagnostic and prognostic utility but also its emerging potential as a therapeutic target to interrupt the cycle of chronic inflammation and fibrosis that drives progression in these interconnected diseases

Therefore, CLC protein and eosinophil lysophospholipases are distinct proteins.93 Lastly, through its lectin-like domains, CLC protein may bind carbohydrates expressed on microorganisms or biological molecules, such as IgE or laminin.94 Many enzymes, in addition to EPO and the RNases (EDN and ECP), have been identified in human eosinophils, granules, and membranes (see Fig

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