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We then explored the relationship between glutathione biosynthesis and the enhanced mortality of drug-resistant Salmonella due to gentamicin in the presence of cystine

Modulation of the Hsp response was shown to be beneficial for diseases associated with protein aggregation since it reduces the protein aggregation itself and diminishes cellular stress and apoptosis ( G93A mice, a fALS model, while reducing the abundance of ubiquitin-positive aggregates in the motor neurons ( Ambroxol, a beta-glucocerebrosidase 2 (GBA2) inhibitor originally indicated as a generic expectorant and mucolytic drug to treat respiratory tract infectious disorders (Nobata et al., 2006), has been recently found to be a potential drug candidate for ALS treatment

Long-term deficiency can lead to serious heart and neurological problems