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That single interaction has downstream effects across several healing pathways: it supports stem-cell migration to injury sites, promotes angiogenesis (like BPC-157, but through a different mechanism), and dampens inflammatory signaling during the repair phase

A deficiency can affect mood and mental health, ranging from mild depression or anxiety through to confusion and, in severe long-term cases, dementia

For example, some researchers have linked microbial transglutaminase with an increased immune response to gluten

Post-gastrectomy, the physiological absorption of VB12 is compromised due to a lack of gastric mucosa necessary for the absorptive process, with VB12 deficiency arising as an inevitable and early metabolic consequence