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Description

Skye SM, Zhu W, Romano KA, Guo CJ, Wang Z, Jia X, Kirsop J, Haag B, Lang JM, DiDonato JA, Tang WHW, Lusis AJ, Rey FE, Fischbach MA, Hazen SL

Redox regulation in cancer stem cells

Included articles described hydroquinone-associated ochronosis

PARP-1 has been found to interact directly with the RBR-type E3 ubiquitin ligase RNF144A, which promotes PARP-1 self-ubiquitination and proteasome-mediated degradation (Zhang et al., 2017), indicating that E3 ligases can also regulate PARP-1 stability in reverse