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Consistent with this, intracellular Myo-Ins concentrations are generally reported to be 5500-fold higher than extracellular levels in mammalian cells 42 , with mid-millimolar estimates in several tissues, supporting the physiological relevance of the 0.15 mM range used in our in vitro fibroblast model

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Furthermore, bilirubin inhibits NADPH oxidase, which serves to keep ROS levels low

Plant Physiol 24:1 Arora M, Saxena P, Abdin MZ, Varma A (2020) Interaction between Piriformospora indica and Azotobacter chroococcum diminish the effect of salt stress in Artemisia annua L