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Moreover, 50 or 100 mg/kg of luteolin has been found to markedly attenuate DSS-induced murine colitis symptoms compared with a DSS group, primarily by inhibiting JNK1/2, phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling, NF-B and STAT3 pathways to exert anti-inflammatory, anti-apoptotic and anti-autophagic effects for colonic homeostasis restoration (68)

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doi: 10.3389/fcvm.2023.1151575

In India, the CDSCO framework under the Drugs and Cosmetics Act covers Schedule H and H1 categories for prescription medicines, but most grey-market peptides are not classified under any schedule at all, creating an effective regulatory absence