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One possibility is that oxidized glutathione directly oxidizes roGFP2 and other reduced proteins, however previous studies (Mller et al., 2017) and the current in vitro and yeast data show that direct roGFP2 oxidation by glutathione is very inefficient

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The architecture of SpNOX The structure of SpNOX corresponds to the canonical NOX structure, with an N-terminal TM domain that coordinates two hemes and a C-terminal DH domain bound to FAD (Fig

The ability of EGCG to synergize with a diverse range of therapeutic agentsspanning from conventional chemotherapies to targeted therapies, immunotherapies, and natural products, underlines its potential as an adjunct in cancer treatment