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AOD 9604 (Anti-Obesity Drug 9604) is the commercial development name given to the HGH fragment spanning amino acids 176 through 191, with a tyrosine substitution at the N-terminus replacing the native phenylalanine for stability

Elevating Sirt1 or NAD + levels could promote the accumulation of PGC1 in the nucleus, which results in the transcription of genes that are necessary for mitochondrial function and biogenesis