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Delivered via pH-sensitive nanoparticles, it is selectively released in the acidic penumbra, where it competitively inhibits mitochondrial SDH, thereby blocking reverse electron transport and reducing ROS, a key trigger of NLRP3 inflammasome activation and lipid peroxidation [218]

Venous thromboembolism in inflammatory bowel disease

Liver Spots Liver spots (chloasma) are patches of pigmentation spread usually symmetrically on either cheeks or on the forehead of women in their 30s and 40s

While mild dehydration might respond to oral rehydration, moderate to severe cases require the rapid replenishment that only IV therapy can provide