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Exploring the pathogenesis of depression and potential antidepressants through the integration of reverse network pharmacology, molecular docking, and molecular dynamics

Start with the right dose: If a vitamin B12 deficiency is diagnosed, doses of 1000 mcg or more are generally recommended

They regulate the development and homeostasis of OPCs and mature oligodendrocytes, thereby directly impacting the myelination process ( + microglial subset predominates in early myelinating regions of the developing brain and expresses genes involved in neuronal and glial survival, migration, and differentiation

1.86 mg g 1 D.W., respectively, Fig