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Corporate Performance & Research Year-end HGIOS reports for 2024/25 and Business Improvement Plans were agreed at the June meeting of Council and published on the Council website The Councils Annual Complaints handling report was also agreed at Council in June 2025 and published on the Council website The Successful annual renewal of the Councils insurance arrangements Improved recording of complaints on the CRM has enabled more comprehensive complaints handling reports to be issued to senior management on a quarterly basis from Q1 25/26 onwards Improved officer guidance for complaints handling was developed for publication and distribution in Q3 25/26 Our performance Framework was updated to include the revised statutory direction and timescales for 25/26 performance reporting Audit Scotland highlighted the Performance pages of the Council website as best practice in supplementary guidance published around meeting the requirements of the new statutory direction Monthly HGIOS reports and regular case studies continued to be published on the Council website assisting with our Public Performance Reporting requirements Publication of the Annual LGBF Benchmarking report which was approved by Council in Q2 Support provided to the Business & Digital Change team in relation to the continued rollout of Oracle fusion An innovative infographic approach was developed for publication of child protection data All annual data returns were completed and submitted to the Scottish Government within target timescales

Consequently, distinct IL-6 pathways govern various biological effects, including regulating white blood cell recruitment, tumor-associated inflammation, and contributing significantly to immune response, hematopoietic function, and acute phase homeostasis [11]