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Testing the toxicity of e-liquid flavoring on cells is extremely important, he says

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Women who smoked were younger and had a higher BMI than controls (Table 1) and their infants had lower birthweights (3,035 490 versus 3,405 598 g, p = 0.005) with a significant dose effect: linear modeling of the nicotine exposed cohort demonstrated that every increase of one cigarette per day was associated with a 41 g reduction in birthweight (95% CI 71 to 11 g, p = 0.010)

When you smoke, nicotine is absorbed into your bloodstream and reaches your brain within seconds