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Selenium Selenium is a cofactor of glutathione peroxidase, an antioxidant enzyme active inside of cells that protects our cells from damage by free radicals produced during metabolism

doi:10.1007/s00508-013-0354-y Schnedl, Wolfgang J et al

Alpha lipoic acid side effects are typically mild and may include: Gastrointestinal symptoms : Nausea, vomiting, abdominal discomfort, or diarrhoea, particularly at higher doses Hypoglycaemia : ALA may lower blood glucose levels, which is beneficial for diabetics but poses a risk if combined with antidiabetic medications

See 21 CFR 73.35,73.50, 73.75, 73.200, 73.275, 73.295, 73.315, respectively