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TISSUE-SPECIFIC FEATURES OF GLUTATHIONE IMPORT TO MITOCHONDRIA Previous studies in a renal proximal tubular cell line, NRK-52E, indicated that overexpression of OGC and DIC increased mGSH levels and protected against oxidant-mediated cell death (Lash et al., 2002

As expected, FoB were clearly detectable in Gclc fl/fl Mb1-Cre + mice by the expression of CD23-ADT and IgD-ADT (Supplementary Fig

Glutathione scavenges free radicals, detoxifies heavy metals, helps ferry amino acids into the cells, helps in bile production, and much more

NF-B translocated into the nucleus activates the transcription of target genes (Basak and Hoffmann 2008)