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JAMA Network Open , 6(11), e2342210

In CUMS mouse models, Kai-Xin-San reduced LPS and pro-inflammatory cytokine levels while increasing tight junction protein expression in the gut and BBB, ameliorating depression-like behaviors through regulation of the gut microbiotainflammationstress system (Cao et al., 2020)

P., Biery, N

These include Cortex eucommiae, Folium artemisiae argyi, Glycyrrhiza uralensis, Euscaphis japonica, Ailanthus altissima, Dioscorea opposite, Angelica sinensis, Atractylodes macrocephala koidz and Scutellaria baicalensis [251]