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It may have neuroprotective effects because of the reduction of oxidative stress in the brain

This is largely due to hormonal changes, including a natural decline in growth hormone and estrogen

The platform enabled efficient loading of an oligo-PROTAC (DFUS-PS9C), conjugated via click chemistry to an E3 ligase ligand, facilitating targeted ubiquitination and degradation of FUS protein, a strategy with significant implications for PROTAC-based therapies in neurodegenerative diseases

Exclusion criteria included recent respiratory infection (within 4 weeks), chronic pulmonary disease, autoimmune or immunodeficiency disorders, and use of systemic or inhaled corticosteroids within 24 h before sampling