oral melanotic macule inside cheek Pigmented Lesions of the Cavity A Black Spot on the

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Most current OA animal models, such as the DMM model or chemically induced models, can simulate cartilage damage in the short term but struggle to fully replicate the long-term cumulative multifactorial pathological changes of human chronic OA

Furthermore, TR-ZRA-treated APP/PS1 mice showed significant improvement in memory deficits