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Blood 103 , 25602567 (2004)

Blocking the HGF/c-Met/mTOR signaling pathway by knocking down the expression of mTOR inhibits PNI of pancreatic cancer To further understand the role of mTOR in the progression of the HGF/c-Met pathway promoting PNI in pancreatic cancer, the lentiviral vector mTOR-shRNA was used to suppress mTOR expression in pancreatic cancer cell lines

The published data show that estrogen-like molecules can mimic or block endogenous estrogens biological effects through a series of non-genomic responses (Park et al., 2012

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