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This direct damage, along with metabolic disturbances and altered gene expression in cardiomyocytes induced by the inflammatory response, results in necrosis and apoptosis of cardiomyocytes (32)

This microbial-host interaction suggests AIEC may promote CD susceptibility by triggering ferroptotic cell death

This indicates that rutin may enhance the toughness of retinal capillaries, diminish their permeability, and alleviate inflammatory stimuli on endothelial cells while preserving the integrity of the vascular wall (Palmitessa et al., 2022)

Preclinical research showed that quercetin supports mitophagy and modulates mitochondrial biogenesis, MMP, oxidative respiration, and ATP anabolism as well as intramitochondrial redox status [50]