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Therefore, the function of Ubp3 on the RQC is still unknown

Weber, E., Lai, Y., Lei, M., Jiang, T

DiCapua Siegel DS, Martin T, Singhal S, Wang M , Vij R, Jakubowiak AJ, Jagannath S, Lonial S, Kukreti V, Bahlis NJ, Alsina M, Chanan-Khan AAA, Buadi F, Reu FJ, Somlo G, Kunkel LA, Rajangam K, Chang YL, Orlowski RZ, Stewart AK, Consortium (MMRC) MR

The most common is a genetic defect in substances referred to as organic anion transporters in the kidney, which leads to an excessive reabsorption of uric acid from the kidney and thus too much uric acid in the blood