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The resulting tryptic peptides were desalted using in-house-crafted SDB-RPS StageTips and 200 ng of peptides were loaded in Evotips (Evosep) according to the manufacturers instructions

Compared to the standard administration of doxorubicin, the concentration over time of DLE administration was approximately five-fold higher for blood and six-fold higher for plasma (Ataullakhanov et al., 1997)

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