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Cancer cells resistant to a wide range of chemo-, targeted- and even immuno-therapies, are particularly susceptible to killing by ferroptosis inducers such as GPX4 inhibitors

Furthermore, the long non-coding (lnc)RNA lnc-MRGPRF-6:1 has been identified as a promoter of ox-LDL-induced macrophage ferroptosis through the inhibition of GSH peroxidase 4, thereby influencing the progression of atherosclerosis (111)