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189 In contrast, from a prophylactic approach, another research group proposed what they deemed a cost-effective approach of yearly injections of 1000 g of vitamin B12 to every patient on metformin to reduce the risk of deficiency and also stated that this could remove the requirement for annual screening, though this has not been empirically tested

10.3390/ijms23010480 12 BirkelandE.GharagozlianS.BirkelandK

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This is important given the rich innervation of the airway and its modulatory role in mucus secretion [14,15,16,17,18,19]