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After injecting bacterial amyloids into the wall of the stomach of mice, aggregates of fluorescent mouse beta-amyloid were found within hours in the enteric nervous system, within a month elsewhere in the gut as well, and within a year in the vagus nerve and brain, including the hippocampus (Sun et al., 2020a)

Biol Psychiatry 81:e19e21

Second they now gain the ability to secrete inflammatory proteins called cytokines that appear to be directly responsible for the destruction of follicles causing decreased ovarian reserve and the damage of mitochondria during egg development leading to poor egg/embryo quality

Its generally advised to alternate retinol and copper peptides to avoid reduced efficacy or irritation