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Furthermore, histopathological observations on both H & E staining and Oil red O staining demonstrated serious hepatic steatosis and cardiac tissue damage with lipid droplets in HM groups contrasted to the control group due to higher lipid profile and increased cellular toxicity marker such as ALT, AST, ALP, LDH and CK-MB level

MASLD-induced changes in antioxidant system To survive in an oxygen-rich environment, aerobic organisms had to develop efficient defense systems of enzymatic and non-enzymatic antioxidants to control the cellular levels of ROS to maintain redox homeostasis (Miao and St Clair 2009

We conducted reverse MR under the same criteria and performed two-sample MR replication analyses using three additional omega-3 GWAS datasets

H., Ngong, J