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Description

Indicated for: Vitamin B12 deficiency

Lancet 2021 Phase 1b (cagri + sema) Enebo et al., n=96, 20 weeks

2.13.1.2 E693del (Osaka) mutation The APP E693-Tg (Osaka) mouse model, which carries the Osaka mutation (APP695) under the control of the mouse prion promoter, expressed comparable levels of mutant human APP and endogenous mouse APP