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Some compounding pharmacies may begin preparing certain compounds ahead of the formal rule based on this interim signal

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2012 (PMID 22129598), which introduced the HGF-dimerization framing, was retracted in 2025 (retraction notice PMID 40312092)

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MET is enriched in the post-synaptic density fraction, and HGF administration induces MET phosphorylation and clustering of synaptic proteins such as GluN2B, CAMK-II, and the glutamatergic -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor GluA1, suggesting a functional connection between glutamatergic synapse and MET signaling (Tyndall and Walikonis, 2006, 2007)

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