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Summary of Questions Many of my technical questions (besides those in my vaccine Fact/Fiction recap ) came after reading the publication entitled Broadly Protective Multivalent OspA Vaccine against Lyme Borreliosis, Developed Based on Surface Shaping of the C-Terminal Fragment . The paper details how Valneva designed the vaccine off of six different outer surface protein A (OspA) derived from the five most common species of Borrelia found in Europe and one species found in the U.S