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Furthermore, acupuncture has been shown to significantly enhance lipid metabolism and the systemic inflammatory response in HFD-induced NAFLD rats, possibly through the regulation of the intestinal microbiota composition [169]

This distinct microbial feature was intimately linked to the observed disturbances in epithelium barrier integrity and pro-inflammatory signaling in the intestine

Suppression of NOD-like receptor protein 3 inflammasome activation and macrophage M1 polarization by hederagenin contributes to attenuation of sepsis-induced acute lung injury in rats