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Common Symptoms of a Sulfa Allergy Can Include: Skin rashes or hives (most common) Fever Swelling of the face, mouth, or tongue Stomach cramps In severe cases, anaphylaxis Drugs commonly linked to Sulfa Allergy: Antibiotics Sulfamethoxazole (Co-trimoxazole, Bactrim, Septra) Sulfadiazine Sulfisoxazole Anti-inflammatory / Autoimmune Sulfasalazine Dapsone Diuretics Thiazides (Hydrochlorothiazide, Chlorthalidone, Indapamide) Loop diuretics (Furosemide, Bumetanide, Torsemide) Carbonic anhydrase inhibitors (Acetazolamide, Dorzolamide, Brinzolamide) Antidiabetic agents Sulfonylureas (Glibenclamide, Glipizide, Glimepiride, Gliclazide) Others Celecoxib (COX-2 inhibitor NSAID) Probenecid Key takeaway: Not every patient with a sulfa allergy will react to all sulfonamide drugs but vigilance saves lives

The pharmaceutical science journal ACS Omega published detailed kinetic modeling of this degradation, confirming that temperature control is the primary factor in preventing DKP-related impurity formation

Therefore, an ASP-based payment limit likely better reflects acquisition cost of the drug than list prices in available compendia, such as WAC

2021 Dec 1 [cited 2024 Nov 23];12(1):412