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CB1 receptors are mainly located in excitatory motor neurons, interneurons, and primary afferent neurons

What Actually Works Heres what the current evidence shows about cagrilintide and CagriSema: Weight loss: REDEFINE 1 participants lost over 20% of body weight on average over 68 weeks meaningfully more than semaglutide alone

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Main Research Findings 1) Administration of cagrilintide to overweight and obese patients was a well tolerated treatment that led to a significant reduction in body weight