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Favism does not occur in all susceptible G6PD individuals, 107 and it is thought that additional genetic factors are involved, presumably related to how fava bean oxidants are metabolized

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Additionally, exposure of monocytes to homocysteine induces tissue factor (TF) expression (Khajuria and Houston, 2000), and exposure of endothelial cells to homocysteine increases TF expression (Fryer et al, 1993), and the activation of factor V to factor Va (Rodgers and Conn, 1990), thus favoring thrombin generation through initiation and propagation of the coagulation cascade

Among the results of blood examination, red blood cell (RBC) count (normal range: male, 4.2-6.3 x 10 6 /L