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In consequence, lipid peroxidation products regulate multiple signaling cascades implicated in apoptosis and inflammation, such as the NF-B pathway, in which reactive aldehydes activate NF-B by promoting IB degradation and phosphorylation-mediated inactivation of anti-apoptotic Bcl-2, thereby enhancing pro-inflammatory signaling [45]

8 Conclusion This review provides a comprehensive overview of the potential of MB in both basic research and clinical applications, with a particular emphasis on its innovative roles in disease diagnosis and therapy