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Approximately 50 mg of frozen cecal content was added to 0.1 mm glass bead-containing tubes (PowerBead Tubes, Qiagen) prefilled with 300 l RLT buffer (RNeasy mini kit, Qiagen) supplemented with -mercaptoethanol (10 l/ml, Sigma-Aldrich) and 1 ml TRIzol (Invitrogen)

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Radiolabeled trials indicate targeted peptide accumulation in the pancreas, liver, and adipose tissue, suggesting precise metabolic activity without systemic toxicity

A single case of dapsone-induced methaemoglobinaemia was treated by continuous methylene blue infusion (Berlin et al., 1985)