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UK researchers interested in these angles should note that GHK-Cus gene-regulatory breadth makes it a viable candidate for investigational use beyond cosmetic applications, though human trial data remain limited outside dermatology

Downregulation of catalase has also been observed in lung, pancreatic, prostate, and skin cancers

Conversely, subsequent research revealed that SOD2 expression tends to increase in advanced, aggressive, and metastatic cancers, as well as in various cell models, highlighting the importance of this enzyme in cancer progression