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In this regard, many antioxidant and detoxifying enzymes, such as GST, SOD, are regulated by neuroprotective NF-E2-related factor 2 (Nrf2), a transcription factor activated by oxidative stress and electrophilic molecules and whose relevance in many ocular diseases including glaucoma has been recently reviewed (Himori et al., 2013) or I/R injury (Wei Y

Thus, the system is even more artificial and the interpretation of results may be impossible because beside the oligodendrocyte damage there is interference with all other proliferating cells

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