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It is plausible that factors that play a role in redox homeostasis may play an impactful role in determining APR-246 sensitivity [48]

The thiol groups (R- SH) undergo deprotonation (loss of H + ), giving the thiolate form R-S -

1F), whereas untransduced Mock T cells with GLUT1OE did not exhibit any of the aforementioned changes when compared to control, illustrating a substantial impact of CAR expression on GLUT1OE mediated metabolic programming (Supplementary Fig