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Characterized by iron toxicity accumulation, phospholipid peroxidation and dysfunctional mitochondria, ferroptosis is intricately linked to the hepatic microenvironment, influencing and being influenced by factors such as iron homeostasis, glucose metabolism, lipid metabolism, amino acid metabolism, and the gut-liver axis

We both worked diligently over the past five years to enable us to have as seamless a transition as possible, in order to continue to build on the tremendous culture and accomplishments our department has realized since breaking ground at CU Anschutz 20 years ago

In parallel, tocopheryl glucoside, a stable, water-soluble derivative of vitamin E, contributes to sustained cellular antioxidant defense by promoting the regeneration of intracellular vitamin E 14

Notably, Rh2 demonstrated good biosafety profile and could mitigate doxorubicin-induced cardiotoxicity by targeting inflammatory damages [187]