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1), the results of which we have described below

Positive cardiovascular outcomes would strengthen the case for dual agonism as a preferred therapeutic approach, particularly in high-risk patients

Peptidase assays Stocks of each reagent were prepared at 4 final concentrations, LLVYAMC (400 M), hs 26S proteasome stock (400 nM), FAT10 (60 M) and NUB1 (60 M), in reaction buffer supplemented with 5 mM ATP