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The upregulation of ser/gly synthesis enzymes has been observed in aggressive radiotherapy treated cancers and was described to increase even further under hypoxia, to produce antioxidants to neutralize reactive oxygen species (ROS) and relieve cellular oxidative stress, thereby promoting the survival of radiotherapy treated cancer cells [6,7,8,9,10,11]

Before you chalk it up to aging or stress, it is worth looking at what your body actually has to work with at the cellular level

the CPZ plus ALC (CPZ+ALC) mice received the cuprizone diet and 300 mg/kg/day ALC by oral gavage for the last three weeks of the study (13)

[Google Scholar] Ahn CH, Choi SH (2015)