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DNA vaccines encoding HSP90 reduce lupus manifestations and prolong survival in lupus-prone mice by inducing tolerogenic dendritic cells and expanding regulatory T cells (Tregs), thereby suppressing autoimmune responses

They concluded that these findings indicate "the possibility of prolonging life span of a cell population and of the whole organism." In 2016, a St

To increase therapeutic efficacy in targeting liver fibrosis, future studies should focus on developing nanocarriers and effective therapeutic strategies