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Once synthesized, MOTS-c is actively transported out of the mitochondria and into the nucleus during conditions like exercise or metabolic stress

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Abbreviations UC: Ulcerative colitis Keap1: Kelch-like ECH-associated protein 1 Nrf2: Nuclear factor erythroid 2-related factor 2 GPX4: Glutathione peroxidase 4 NQO1: NAD(P)H quinone dehydrogenase 1 MUC2: Mucin 2 GSH: Glutathione ROS: Reactive oxygen species xCT: Cystine/glutamate antiporter FTH1: Ferritin heavy chain 1 MDA: Malondialdehyde References Buie, M

However, Fenske says, it's relatively easy to tell the difference between a malignant tumor and a benign one