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Although NADPH is unable to translocate to the mitochondria across the inner membrane, its exchange between the cytosol and mitochondria is achieved by NADPH shuttle functions through the enzymes isocitrate dehydrogenase 1, [NADP +] (IDH1), and isocitrate dehydrogenase [NADP] mitochondrial (IDH2) (White et al

Some people may notice changes faster, while others may need more time depending on the issue being researched

Notably, host peroxisome proliferator-activated receptor gamma (PPAR-), a lipid-activated nuclear receptor, is upregulated in Mtb-infected Ms via TLR2 signaling, promoting lipid droplet biogenesis and bacterial survival (195197)

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